Le Retatrutide (LY3437943) is a triple-agonist research peptide developed for the simultaneous study of the GLP-1R, GIPR, and glucagon receptor (GCGR) signaling pathways. This triagonist offers researchers a unique tool for the comparative analysis of metabolic cascades involving all three incretin receptors within a unified in vitro model.
Structurally, retatrutide features a peptide backbone with simulated post-translational modifications — notably side-chain acylation — enabling controlled differential affinity toward the three receptor targets. Its binding profile presents analytical value in ligand-receptor competition and allosteric regulation studies.
CAS Number: 2381002-86-2
Molecular Formula: C₂₃₀H₃₄₁N₄₉O₆₉S
Format: Lyophilized powder — reconstitution required prior to analytical use
Purity: ≥ 98% (HPLC) Storage: -20 °C
COA: Available / link on this page
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