Mazdutide (IBI362) is a third-generation structural analog of oxyntomodulin (OXM), designed for the study of simultaneous interactions with the GLP-1R and GCGR (glucagon receptor). This dual-agonist peptide is of particular interest in research on central energy regulation mechanisms, notably at the level of the hypothalamic-pituitary axis. Its structure comprises a 31-amino-acid backbone with strategic substitutions that enhance receptor selectivity and conformational stability in vitro. Mazdutide serves as a reference compound for comparative studies between mono-selective GLP-1R ligands and mixed GLP-1R/GCGR agonists.
Format: Lyophilized powder — reconstitution required prior to analytical use
Purity: ≥ 98% (HPLC)
Storage: -20 °C
COA: Available / link on this page
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